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1

Direct α-Functionalization of Saturated Cyclic Amines

Dr. Emily A. Mitchell, Dr. Aldo Peschiulli, Dr. Nicolas Lefevre, Dr. Lieven Meerpoel, Prof. Dr. Bert U. W. Maes

Journal:

Chemistry - A European Journal

Year:

2012

Language:

english

File:

PDF, 2.25 MB

english, 2012

2

Cobalt-Catalyzed Diastereoselective Synthesis of C -Furanosides. Total Synthesis of (−)-Isoaltholactone

Nicolas, Lionel, Izquierdo, Eva, Angibaud, Patrick, Stansfield, Ian, Meerpoel, Lieven, Reymond, Sébastien, Cossy, Janine

Journal:

Journal of Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 541 KB

english, 2013

3

Triphenylphosphine: a catalyst for the synthesis of C-aryl furanosides from furanosyl halides

Nicolas, Lionel, Angibaud, Patrick, Stansfield, Ian, Meerpoel, Lieven, Reymond, Sébastien, Cossy, Janine

Journal:

Tetrahedron Letters

Year:

2014

Language:

english

File:

PDF, 279 KB

english, 2014

4

C-2 Arylation of Piperidines through Directed Transition-Metal-Catalyzed sp3 CH Activation

Dr. Hana Prokopcová, Dr. Sheba D. Bergman, Dr. Karel Aelvoet, Veerle Smout, Prof. Dr. Wouter Herrebout, Prof. Dr. Benjamin Van der Veken, Dr. Lieven Meerpoel, Prof. Dr. Bert U. W. Maes

Journal:

Chemistry - A European Journal

Year:

2010

Language:

english

File:

PDF, 220 KB

english, 2010

5

Pyrrolo[1,2-a][1,4]benzodiazepine: A Novel Class of Non-azole anti-Dermatophyte Antifungal Agents.

Lieven Meerpoel, Jef Van Gestel, Frans Van Gerven, Filip Woestenborghs, Patrick Marichal, Vic Sipido, Gilkerson Terence, Roger Nash, David Corens, Ray D. Richards

Journal:

Year:

2005

File:

PDF, 12 KB

2005

6

Synthesis and in vitro and in vivo Antifungal Activity of the Hydroxy Metabolites of Saperconazole

Lieven Meerpoel, Jan Heeres, Leo J. J. Backx, Louis J. E. Van der Veken, Rob Hendrickx, David Corens, Alex De Groot, Stef Leurs, Luc Van der Eycken, Johan Weerts, Paul Luyts, Frans Van Gerven, Filip A

Journal:

Year:

2010

Language:

english

File:

PDF, 344 KB

english, 2010

7

Face selectivity of the Diels-Alder additions and cheletropic additions of sulfur dioxide to 2- vinyl-7-oxabicyclo[2.2.1]hept-2-ene derivatives

Lieven Meerpoel, Maria-Miranda Vrahami, Brigitte Deguin, Pierre Vogel

Journal:

Helvetica Chimica Acta

Year:

1994

Language:

english

File:

PDF, 877 KB

english, 1994

8

Homochiral matching in the Diels-Alder cyclodimerization of 2-vinyl-7-oxabicyclo[2.2.1]hept-2-ene derivatives

Lieven Meerpoel, Maria-Miranda Vrahami, Jacek Ancerewicz, Pierre Vogel

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 339 KB

english, 1994

9

Liquid chromatography–mass spectrometry with chemiluminescent nitrogen detection for on-line quantitative analysis of compound collections: advantages and limitations

David Corens, Michel Carpentier, Marc Schroven, Lieven Meerpoel

Journal:

Journal of Chromatography A

Year:

2004

Language:

english

File:

PDF, 443 KB

english, 2004

10

Pyrrolo[1,2-a][1,4]benzodiazepine: A novel class of non-azole anti-dermatophyte anti-fungal agents

Lieven Meerpoel, Jef Van Gestel, Frans Van Gerven, Filip Woestenborghs, Patrick Marichal, Vic Sipido, Gilkerson Terence, Roger Nash, David Corens, Ray D. Richards

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 326 KB

english, 2005

11

Synthesis of 6-methoxy- and 6-chloro-2(1H)-pyridinone acyclo-C-Nucleosides from 2H-1,4-oxazin-2-ones.

Lieven Meerpoel, Gert J. Joly, Georges J. Hoornaert

Journal:

Year:

1993

Language:

english

File:

PDF, 1.22 MB

english, 1993

12

C-Glycosides and C-disaccharide precursors through carbonylative Stille coupling reactions

Vincent Jeanneret, Lieven Meerpoel, Pierre Vogel

Journal:

Tetrahedron Letters

Year:

1997

Language:

english

File:

PDF, 225 KB

english, 1997

13

Synthesis and Anti-Angiogenic Activity of 6-(1,2,4-Thiadiazol-5-yl)-3-amino pyridazine Derivatives

Jean-Pierre Bongartz, Raymond Stokbroekx, Marcel Van der Aa, Marcel Luyckx, Marc Willems, Marc Ceusters, Lieven Meerpoel, Gerda Smets, Tine Jansen, Walter Wouters, Charlie Bowden, Lisa Valletta, Mark

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 93 KB

english, 2002

14

The Synthesis of 3-Functionalized 5-chloro-6-methyl-2H-1,4-oxazin-2-ones and of pyridines from cycloaddition-elimination reactions with substituted acetylenic compounds.

Koen J. Van Aken, Gerrit M. Lux, Geert G. Deroover, Lieven Meerpoel, Georges J. Hoornaert

Journal:

Year:

1994

Language:

english

File:

PDF, 987 KB

english, 1994

15

An approach to acyclo-1-deazathymidine c-nucleosides via 3,5-dichloro-6-methyl-2H-1,4-oxazin-2-one.

Lieven Meerpoel, Suzanne M. Toppet, Frans Compernolle, Georges J. Hoornaert

Journal:

Year:

1991

Language:

english

File:

PDF, 886 KB

english, 1991

16

Functionalisation in position 3 of 3,5-dichloro-2H-1,4-oxazin-2-ones

Koen J. Van Aken, Lieven Meerpoel, Georges J. Hoornaert

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 274 KB

english, 1992

17

Corrigendum to “Synthesis and anti-angiogenic activity of 6-(1,2,4-thiadiazol-5-yl)-3-amino pyridazine derivatives” [Bioorg. Med. Chem. Lett. 12 (2002) 589]

Jean-Pierre Bongartz, Raymond Stokbroekx, Marcel Van der Aa, Marcel Luyckx, Marc Willems, Marc Ceusters, Lieven Meerpoel, Gerda Smets, Tine Jansen, Walter Wouters, Charlie Bowden, Lisa Valletta, Mark

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 65 KB

english, 2002

18

A fungicidal piperazine-1-carboxamidine induces mitochondrial fission-dependent apoptosis in yeast

Anna Bink, Gilmer Govaert, Isabelle E.J.A. François, Klaartje Pellens, Lieven Meerpoel, Marcel Borgers, Geert Van Minnebruggen, Valérie Vroome, Bruno P.A. Cammue, Karin Thevissen

Journal:

FEMS Yeast Research

Year:

2010

Language:

english

File:

PDF, 158 KB

english, 2010

19

The Role of the Alcohol and Carboxylic Acid in Directed Ruthenium-Catalyzed C(sp3)H α-Alkylation of Cyclic Amines

Dr. Sheba D. Bergman, Dr. Thomas E. Storr, Dr. Hana Prokopcová, Dr. Karel Aelvoet, Gaston Diels, Dr. Lieven Meerpoel, Prof. Dr. Bert U. W. Maes

Journal:

Chemistry - A European Journal

Year:

2012

Language:

english

File:

PDF, 625 KB

english, 2012

20

Outsourcing to exploit a key asset

Lieven Meerpoel, Marc Schroven, Koen Goris, Koen Demoen, Siobhan Marsden

Journal:

Drug Discovery Today

Year:

2006

Language:

english

File:

PDF, 1.47 MB

english, 2006

21

Two-Step One-Pot Synthesis of Benzoannulated Spiroacetals by Suzuki–Miyaura Coupling/Acid-Catalyzed Spiroacetalization

Butkevich, Alexey N., Corbu, Andrei, Meerpoel, Lieven, Stansfield, Ian, Angibaud, Patrick, Bonnet, Pascal, Cossy, Janine

Journal:

Organic Letters

Year:

2012

Language:

english

File:

PDF, 319 KB

english, 2012

22

Cover Picture: Direct α-Functionalization of Saturated Cyclic Amines / Two-Dimensional Oxides: Multifunctional Materials for Advanced Technologies / Permanent Porous Materials from Discrete Organic Molecules—Towards Ultra-High Surface Areas / Fluorescent Microporous Organic Polymers: Potential Testbed for Optical Applications / Soft X-ray Imaging and Spectromicroscopy: New Insights in Chemical State and Morphology of the Key Components in Operating Fuel-Cells / Protein Engineering of Stereoselective Baeyer–Villiger Monooxygenases / Merging Organocatalysis and Gold Catalysis—A Critical Evaluation of the Underlying Concepts / Supramolecular-Tilt-Chirality on Twofold Helical Assemblies / C

Dr. Emily A. Mitchell, Dr. Aldo Peschiulli, Dr. Nicolas Lefevre, Dr. Lieven Meerpoel, Prof. Dr. Bert U. W. Maes, Prof. Gianfranco Pacchioni, Dr. Michael Mastalerz, Dr. Abhijit Patra, Prof. Dr. Ullrich

Journal:

Chemistry - A European Journal

Year:

2012

Language:

english

File:

PDF, 1.76 MB

english, 2012

23

ChemInform Abstract: Intramolecular Sila-Matteson Rearrangement: A General Access to Silylated Heterocycles.

Cyril Francois, Thomas Boddaert, Muriel Durandetti, Olivier Querolle, Luc Van Hijfte, Lieven Meerpoel, Patrick Angibaud, Jacques Maddaluno

Journal:

Year:

2012

File:

PDF, 41 KB

2012

24

Diastereoselective Metal-Catalyzed Synthesis of C -Aryl and C -Vinyl Glycosides

Nicolas, Lionel, Angibaud, Patrick, Stansfield, Ian, Bonnet, Pascal, Meerpoel, Lieven, Reymond, Sébastien, Cossy, Janine

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 480 KB

english, 2012

25

Diastereoselective Metal-Catalyzed Synthesis of C -Aryl and C -Vinyl Glycosides

Nicolas, Lionel, Angibaud, Patrick, Stansfield, Ian, Bonnet, Pascal, Meerpoel, Lieven, Reymond, Sébastien, Cossy, Janine

Journal:

Angewandte Chemie

Year:

2012

Language:

english

File:

PDF, 473 KB

english, 2012

26

ChemInform Abstract: Direct α-Functionalization of Saturated Cyclic Amines

Mitchell, Emily A., Peschiulli, Aldo, Lefevre, Nicolas, Meerpoel, Lieven, Maes, Bert U. W.

Journal:

Year:

2012

File:

PDF, 19 KB

2012

27

Tandem Suzuki-Miyaura Coupling/Acid-Catalyzed Cyclization between Vinyl Ether Boronates and Vinyl Halides: A Concise Approach to Polysubstituted Furans

Butkevich, Alexey N., Meerpoel, Lieven, Stansfield, Ian, Angibaud, Patrick, Corbu, Andrei, Cossy, Janine

Journal:

Organic Letters

Year:

2013

Language:

english

File:

PDF, 321 KB

english, 2013

28

Copper-catalysed amidation of 2-chloro-pyridines

Nicolas, Lionel, Angibaud, Patrick, Stansfield, Ian, Meerpoel, Lieven, Reymond, Sébastien, Cossy, Janine

Journal:

Year:

2013

Language:

english

File:

PDF, 484 KB

english, 2013

29

Removal of the Pyridine Directing Group from α-Substituted N -(Pyridin-2-yl)piperidines Obtained via Directed Ru-Catalyzed sp 3 C–H Functionalization

Smout, Veerle, Peschiulli, Aldo, Verbeeck, Stefan, Mitchell, Emily A., Herrebout, Wouter, Bultinck, Patrick, Vande Velde, Christophe M. L., Berthelot, Didier, Meerpoel, Lieven, Maes, Bert U. W.

Journal:

Journal of Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 717 KB

english, 2013

30

Directed Ruthenium-Catalyzed C( sp 3 )H α-Alkylation of Cyclic Amines Using Dioxolane-Protected Alkenones

Kulago, Artem A., Van Steijvoort, Ben F., Mitchell, Emily A., Meerpoel, Lieven, Maes, Bert U. W.

Journal:

Advanced Synthesis & Catalysis

Year:

2014

Language:

english

File:

PDF, 581 KB

english, 2014

31

Ruthenium-Catalyzed α-(Hetero)Arylation of Saturated Cyclic Amines: Reaction Scope and Mechanism

Peschiulli, Aldo, Smout, Veerle, Storr, Thomas E., Mitchell, Emily A., Eliáš, Zdeněk, Herrebout, Wouter, Berthelot, Didier, Meerpoel, Lieven, Maes, Bert U. W.

Journal:

Chemistry - A European Journal

Year:

2013

Language:

english

File:

PDF, 457 KB

english, 2013

32

Synthesis and in Vitro and in Vivo Structure−Activity Relationships of Novel Antifungal Triazoles for Dermatology

Meerpoel, Lieven, Backx, Leo J. J., Van der Veken, Louis J. E., Heeres, Jan, Corens, David, De Groot, Alex, Odds, Frank C., Van Gerven, Frans, Woestenborghs, Filip A. A., Van Breda, Andre, Oris, Miche

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 169 KB

english, 2005

33

Cycloaddition of 3-Amino-5-chloro-2(1 H )-pyrazinones and Olefins: Ring Transformation into 3-Amino- or 6-Cyano-Substituted 2-Pyridinone Systems

Vandenberghe, Stef M., Buysens, Kris J., Meerpoel, Lieven, Loosen, Patrick K., Toppet, Suzanne M., Hoornaert, Georges J.

Journal:

Journal of Organic Chemistry

Year:

1996

Language:

english

File:

PDF, 296 KB

english, 1996

34

Intramolecular Sila-Matteson Rearrangement: A General Access to Silylated Heterocycles

François, Cyril, Boddaert, Thomas, Durandetti, Muriel, Querolle, Olivier, Van Hijfte, Luc, Meerpoel, Lieven, Angibaud, Patrick, Maddaluno, Jacques

Journal:

Organic Letters

Year:

2012

Language:

english

File:

PDF, 399 KB

english, 2012

35

ChemInform Abstract: Directed Ruthenium-Catalyzed C(sp 3 )-H α-Alkylation of Cyclic Amines Using Dioxolane-Protected Alkenones.

Kulago, Artem A., Van Steijvoort, Ben F., Mitchell, Emily A., Meerpoel, Lieven, Maes, Bert U. W.

Journal:

Year:

2014

File:

PDF, 34 KB

2014

36

Synthesis of Novel Isothiazole and Isothiazolo[4,5- d ] Pyrimidine Analogues of the Natural C -Nucleosides Pyrazofurin and the Formycins

Buffel, Diederik K., Meerpoel, Lieven, Toppet, Suzanne M., Hoornaert, Georges J.

Journal:

Nucleosides and Nucleotides

Year:

1994

Language:

english

File:

PDF, 872 KB

english, 1994

37

Anionic Access to Silylated and Germylated Binuclear Heterocycles

Boddaert, Thomas, François, Cyril, Mistico, Laetitia, Querolle, Olivier, Meerpoel, Lieven, Angibaud, Patrick, Durandetti, Muriel, Maddaluno, Jacques

Journal:

Chemistry - A European Journal

Year:

2014

Language:

english

File:

PDF, 388 KB

english, 2014

38

A General Synthesis of 3,5-Dihalo-2 H -1,4-oxazin-2-ones from Cyanohydrins

Meerpoel, Lieven, Hoornaert, Georges

Journal:

Year:

1990

File:

PDF, 321 KB

1990

39

Iron-Catalyzed Synthesis of C2 Aryl- and N -Heteroaryl-Substituted Tetrahydropyrans

Bosset, Cyril, Angibaud, Patrick, Stanfield, Ian, Meerpoel, Lieven, Berthelot, Didier, Guérinot, Amandine, Cossy, Janine

Journal:

Journal of Organic Chemistry

Year:

2015

Language:

english

File:

PDF, 1.19 MB

english, 2015

40

Synthesis and orthogonal functionalization of oxazolo[5′,4′:4,5]pyrano[2,3-b]pyridine by intra- and intermolecular Pd-catalyzed direct C–H bond heteroarylation

Théveau, Laure, Schneider, Cédric, Querolle, Olivier, Meerpoel, Lieven, Levacher, Vincent, Hoarau, Christophe

Journal:

Organic & Biomolecular Chemistry

Year:

2016

Language:

english

File:

PDF, 976 KB

english, 2016

41

ChemInform Abstract: Synthesis of Substituted Indenones and Indanones by a Suzuki-Miyaura Coupling/Acid-Promoted Cyclization Sequence.

Butkevich, Alexey N., Ranieri, Beatrice, Meerpoel, Lieven, Stansfield, Ian, Angibaud, Patrick, Corbu, Andrei, Cossy, Janine

Journal:

Year:

2014

File:

PDF, 23 KB

2014

42

ChemInform Abstract: Anionic Access to Silylated and Germylated Binuclear Heterocycles.

Boddaert, Thomas, Francois, Cyril, Mistico, Laetitia, Querolle, Olivier, Meerpoel, Lieven, Angibaud, Patrick, Durandetti, Muriel, Maddaluno, Jacques

Journal:

Year:

2015

File:

PDF, 27 KB

2015

43

ChemInform Abstract: Tandem Suzuki-Miyaura Coupling/Acid-Catalyzed Cyclization Between Vinyl Ether Boronates and Vinyl Halides: A Concise Approach to Polysubstituted Furans.

Butkevich, Alexey N., Meerpoel, Lieven, Stansfield, Ian, Angibaud, Patrick, Corbu, Andrei, Cossy, Janine

Journal:

Year:

2013

File:

PDF, 38 KB

2013

44

ChemInform Abstract: Diastereoselective Metal-Catalyzed Synthesis of C-Aryl and C-Vinyl Glycosides.

Nicolas, Lionel, Angibaud, Patrick, Stansfield, Ian, Bonnet, Pascal, Meerpoel, Lieven, Reymond, Sebastien, Cossy, Janine

Journal:

Year:

2013

File:

PDF, 40 KB

2013

45

ChemInform Abstract: Cobalt-Catalyzed Diastereoselective Synthesis of C-Furanosides. Total Synthesis of (-)-Isoaltholactone.

Nicolas, Lionel, Izquierdo, Eva, Angibaud, Patrick, Stansfield, Ian, Meerpoel, Lieven, Reymond, Sebastien, Cossy, Janine

Journal:

Year:

2014

File:

PDF, 24 KB

2014

46

ChemInform Abstract: Triphenylphosphine: A Catalyst for the Synthesis of C-Aryl Furanosides from Furanosyl Halides.

Nicolas, Lionel, Angibaud, Patrick, Stansfield, Ian, Meerpoel, Lieven, Reymond, Sebastien, Cossy, Janine

Journal:

Year:

2014

File:

PDF, 28 KB

2014

47

ChemInform Abstract: Iron-Catalyzed Synthesis of C2 Aryl- and N-Heteroaryl-Substituted Tetrahydropyrans.

Bosset, Cyril, Angibaud, Patrick, Stanfield, Ian, Meerpoel, Lieven, Berthelot, Didier, Guerinot, Amandine, Cossy, Janine

Journal:

Year:

2016

File:

PDF, 29 KB

2016

48

ChemInform Abstract: Two-Step One-Pot Synthesis of Benzoannulated Spiroacetals by Suzuki-Miyaura Coupling/Acid-Catalyzed Spiroacetalization.

Butkevich, Alexey N., Corbu, Andrei, Meerpoel, Lieven, Stansfield, Ian, Angibaud, Patrick, Bonnet, Pascal, Cossy, Janine

Journal:

Year:

2013

Language:

english

File:

PDF, 46 KB

english, 2013

49

ChemInform Abstract: Ruthenium-Catalyzed α-(Hetero)arylation of Saturated Cyclic Amines: Reaction Scope and Mechanism.

Peschiulli, Aldo, Smout, Veerle, Storr, Thomas E., Mitchell, Emily A., Elias, Zdenek, Herrebout, Wouter, Berthelot, Didier, Meerpoel, Lieven, Maes, Bert U. W.

Journal:

Year:

2013

File:

PDF, 39 KB

2013

50

Access to Silylated Pyrazole Derivatives by Palladium-Catalyzed C−H Activation of a TMS group

Mistico, Laetitia, Querolle, Olivier, Meerpoel, Lieven, Angibaud, Patrick, Durandetti, Muriel, Maddaluno, Jacques

Journal:

Chemistry - A European Journal

Year:

2016

Language:

english

File:

PDF, 575 KB

english, 2016